Why 11-cis-Retinal? Why Not 7-cis-, 9-cis-, or 13-cis-Retinal in the Eye?
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چکیده
منابع مشابه
Bathorhodopsin intermediates from 11-cis-rhodopsin and 9-cis-rhodopsin.
Bathorhodopsin-rhodopsin difference spectra of native 11-cis-rhodopsin and regenerated 9-cis-rhodopsin were measured at room temperature with a double-beam laser spectrophotometer after excitation at 532 nm. A detailed analysis of data obtained at 85 psec after excitation suggests that the bathorhodopsins generated from 11-cis- and 9-cis-rhodopsin differ in their extinction coefficients and tha...
متن کاملPartial agonist activity of 11-cis-retinal in rhodopsin mutants.
Rhodopsin, the photoreceptor molecule of the vertebrate rod cell, is a G protein-coupled receptor. Rhodopsin consists of the opsin apoprotein and its 11-cis-retinal chromophore, which is covalently bound to a specific lysine residue by a stable protonated Schiff base linkage. Rhodopsin activation occurs when light causes photoisomerization of the 11-cis chromophore to its all-trans form. The al...
متن کاملFar-infrared vibrational spectra of all-trans, 9-cis and 13-cis retinal measured by THz time-domain spectroscopy
Low-frequency torsional vibration modes of the conjugated polyene chain of the biologically important chromophore retinal are of major relevance when studying its photoisomerization dynamics. We present absorptivity and dispersion spectra of three dierent retinal isomers in the far-infrared region between 10 and 100 cmÿ1 (0.3±3.0 THz) measured by terahertz time-domain spectroscopy at 298 and 1...
متن کاملChromophore switch from 11-cis-dehydroretinal (A2) to 11-cis-retinal (A1) decreases dark noise in salamander red rods.
Dark noise, light-induced noise and responses to brief flashes of light were recorded in the membrane current of isolated rods from larval tiger salamander retina before and after bleaching most of the native visual pigment, which mainly has the 11-cis-3,4-dehydroretinal (A2) chromophore, and regenerating with the 11-cis-retinal (A1) chromophore in the same isolated rods. The purpose was to tes...
متن کاملSolubility of Cis, Cis-Muconic Acid in Various Polar Solvents from 298.15 K to 348.15 K
The present work concerns with an investigation on the solubility of cis,cis-muconic acid dissolution in different polar solvents by characterizing and modeling the dissolution as a function of temperature. Water, ethanol, 2-propanol and acetic acid have been investigated as solvents in the range temperatures from a 298.15 to 348.15 K. Owing to the absence of cis,cis-muconic acid solubility...
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ژورنال
عنوان ژورنال: Journal of the American Chemical Society
سال: 2011
ISSN: 0002-7863,1520-5126
DOI: 10.1021/ja208789h